INT346573

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Sh3gl3) endosome (Sh3gl3) cytoplasm (Sh3gl3)
Sh3gl3 (Mus musculus)
Pain Link Frequency Relevance Heat
hypoalgesia 1 82.40 Quite High
peripheral neuropathy 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Neuropathic pain 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoalagesia 1 82.40 Quite High
Nociception 3 61.76 Quite High
Neuropathic Pain 3 53.56 Quite High
Fabry Disease 18 45.56 Quite Low
Disease 11 5.00 Very Low Very Low Very Low
Gauchers Disease 7 5.00 Very Low Very Low Very Low
Peripheral Neuropathy 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Cerebrovascular Disease 2 5.00 Very Low Very Low Very Low
Disease Progression 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Collectively, these results in the Fabry mouse suggest that SRT with eliglustat tartrate can provide benefit by delaying GL-3 accumulation and its attendant (renal and neurologic) symptoms.
GL-3 Binding (accumulation) of
1) Confidence 0.14 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2991350 Disease Relevance 0.20 Pain Relevance 0.08

General Comments

This test has worked.

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