INT346575

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.58
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (Rraga) Golgi apparatus (Rraga) nucleus (Rraga)
lysosome (Rraga) cytoplasm (Rraga)
Rraga (Mus musculus)
Pain Link Frequency Relevance Heat
peripheral neuropathy 6 72.76 Quite High
Neuropathic pain 4 60.64 Quite High
Peripheral nervous system 4 37.92 Quite Low
Spinal cord 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
hypoalgesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 22 86.44 High High
Peripheral Neuropathy 6 72.76 Quite High
Neuropathic Pain 6 60.64 Quite High
Fabry Disease 36 59.52 Quite High
Targeted Disruption 4 52.56 Quite High
Gauchers Disease 14 48.72 Quite Low
Diarrhoea 2 9.96 Low Low
Nociception 6 5.00 Very Low Very Low Very Low
Cerebrovascular Disease 4 5.00 Very Low Very Low Very Low
Disease Progression 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-gal elicited the production of antibodies against the recombinant human enzyme (that may complicate interpretation of the results), studies that involved the use of ERT were performed using the Fabry-Rag mouse model, which does not generate a humoral response to recombinant human ?
Regulation (using) of Fabry-Rag
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2991350 Disease Relevance 0.45 Pain Relevance 0.04
The reductions in all treatment groups were significant relative to the untreated Fabry-Rag control.
Regulation (control) of Fabry-Rag
2) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2991350 Disease Relevance 0.13 Pain Relevance 0.09

General Comments

This test has worked.

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