INT346597

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Sh3gl3) endosome (Sh3gl3) cellular_component (Sh2d1b2)
cytoplasm (Sh3gl3)
Sh3gl3 (Mus musculus)
Sh2d1b2 (Mus musculus)
Pain Link Frequency Relevance Heat
peripheral neuropathy 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Neuropathic pain 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
hypoalgesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fabry Disease 18 5.00 Very Low Very Low Very Low
Disease 11 5.00 Very Low Very Low Very Low
Gauchers Disease 7 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Peripheral Neuropathy 3 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Cerebrovascular Disease 2 5.00 Very Low Very Low Very Low
Disease Progression 2 5.00 Very Low Very Low Very Low
Heart Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these results suggest that in all the tissues tested, maximum GL-3 reduction can be obtained using a combination of ERT plus SRT, and that within this context, more frequent dosing with enzyme appears to be more effective.


GL-3 Binding (combination) of ERT
1) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2991350 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

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