INT346707

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (PAX6) nucleolus (PAX6) nucleus (PAX6)
DNA binding (PAX6) transcription factor binding (PAX6) cytoplasm (PAX6)
Anatomy Link Frequency
somatic cells 2
PAX6 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 4 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 60 99.84 Very High Very High Very High
Subependymal Glioma 31 50.00 Quite Low
Aniridia 14 50.00 Quite Low
Glioma 8 31.36 Quite Low
Inborn Genetic Diseases 4 5.00 Very Low Very Low Very Low
Brain Tumor 4 5.00 Very Low Very Low Very Low
Glioblastoma 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Chromosome Aberrations 2 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results show that the tumor genome has two distinct PAX6 deletions (Table 1): the one is the same to that of normal somatic cells (albeit we did not examine whether the 5?
Negative_regulation (has) of Gene_expression (deletions) of PAX6 in somatic cells associated with cancer
1) Confidence 0.37 Published 2010 Journal Brain Pathology (Zurich, Switzerland) Section Body Doc Link PMC2991767 Disease Relevance 0.50 Pain Relevance 0

General Comments

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