INT346807

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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Egr1) intracellular (Egr1) DNA binding (Egr1)
transcription factor binding (Egr1) cytoplasm (Egr1)
Anatomy Link Frequency
hippocampus 2
Egr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 25 99.20 Very High Very High Very High
long-term potentiation 3 5.00 Very Low Very Low Very Low
behavioral therapy 2 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 1 5.00 Very Low Very Low Very Low
Pyramidal cell 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 9 98.56 Very High Very High Very High
Cognitive Disorder 21 5.00 Very Low Very Low Very Low
Targeted Disruption 5 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Amnesia 3 5.00 Very Low Very Low Very Low
Intellectual Impairment 3 5.00 Very Low Very Low Very Low
Aids-related Complex 2 5.00 Very Low Very Low Very Low
Syndrome 2 5.00 Very Low Very Low Very Low
Post-traumatic Stress Disorder 2 5.00 Very Low Very Low Very Low
Shock 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, dissociations have also been shown; for example, in a fear conditioning task, it was shown, using oligonucleotide antisense, that regulation of the transcription factor, Zif268/Egr1 in CA1 of the hippocampus was not necessary for consolidating fear memory, but was necessary for reconsolidation of the active memory (Lee et al., 2004).
Regulation (regulation) of Transcription (transcription) of Zif268 in hippocampus associated with anxiety disorder and hippocampus
1) Confidence 0.44 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2992451 Disease Relevance 0.27 Pain Relevance 0.09

General Comments

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