INT346836

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (MECP2, PTGS2) small molecule metabolic process (PTGS2) endoplasmic reticulum (PTGS2)
enzyme binding (PTGS2) DNA binding (MECP2) protein complex (PTGS2)
Anatomy Link Frequency
monocytes 1
MECP2 (Homo sapiens)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 1 97.12 Very High Very High Very High
Cancer 18 66.72 Quite High
Breast Cancer 29 60.20 Quite High
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Aggression 1 5.00 Very Low Very Low Very Low
Solid Tumor 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, in vitro studies indicate possible functional effects of the SNPs rs689466 and rs20417 on PTGS2 promoter activity (evaluated by a luciferase gene reporter system) [9,10] and on COX-2 activity (evaluated by PGE2 production in human monocytes) [47].
rs689466 Spec (possible) Regulation (effects) of PTGS2 in monocytes
1) Confidence 0.00 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2992523 Disease Relevance 0.34 Pain Relevance 0

General Comments

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