INT34707

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Context Info
Confidence 0.42
First Reported 1988
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.45
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Nkx6-2) nucleus (Nkx6-2) DNA binding (Nkx6-2)
Anatomy Link Frequency
brain 1
autonomic nervous system 1
Nkx6-2 (Mus musculus)
Pain Link Frequency Relevance Heat
sodium channel 2 96.92 Very High Very High Very High
tetrodotoxin 3 95.96 Very High Very High Very High
Glutamate receptor 1 94.76 High High
agonist 1 93.48 High High
Intracerebroventricular 1 90.84 High High
Eae 2 75.92 Quite High
gABA 3 57.84 Quite High
Glutamate 3 56.64 Quite High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Poisoning 2 99.50 Very High Very High Very High
Sialorrhea 1 97.08 Very High Very High Very High
Vomiting 2 96.40 Very High Very High Very High
Heart Rate Under Development 1 95.84 Very High Very High Very High
Injury 1 62.24 Quite High
Paralysis 1 46.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that GTX-III may elicit its depressant action on horizontal locomotion possibly through interacting with central glutamatergic neurons rather than activating voltage-sensitive sodium channels in the brain.
GTX-III Binding (interacting) of in brain associated with sodium channel
1) Confidence 0.42 Published 1988 Journal Neuropharmacology Section Abstract Doc Link 3070432 Disease Relevance 0.06 Pain Relevance 0.44
Mad honey poisoning caused by grayanotoxin (GTX) is associated with autonomic nervous system symptoms, such as excessive perspiration, hypersalivation, vomiting, and bradycardia.
GTX Binding (associated) of in autonomic nervous system associated with heart rate under development, sialorrhea, vomiting and poisoning
2) Confidence 0.15 Published 2010 Journal Neurotoxicology Section Abstract Doc Link 20038438 Disease Relevance 0.39 Pain Relevance 0.06

General Comments

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