INT34714

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.66
First Reported 1988
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 6
Disease Relevance 2.78
Pain Relevance 1.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (B2m) extracellular region (B2m) molecular_function (B2m)
B2m (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 20 99.04 Very High Very High Very High
Analgesic 4 96.12 Very High Very High Very High
Hippocampus 24 88.56 High High
Inflammation 8 77.88 Quite High
ischemia 32 5.00 Very Low Very Low Very Low
metalloproteinase 8 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 152 100.00 Very High Very High Very High
Albuminuria 2 79.24 Quite High
Apoptosis 8 78.64 Quite High
Nephrosis 2 77.92 Quite High
INFLAMMATION 8 77.88 Quite High
Nephrotoxicity 2 75.00 Quite High
Injury 8 74.40 Quite High
Cv Unclassified Under Development 24 5.00 Very Low Very Low Very Low
Hypoxia 12 5.00 Very Low Very Low Very Low
Asphyxia 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Though not significant, there is a trend for B2m mRNA upregulation at 7 days after treatment too (Fig. 4).


Positive_regulation (upregulation) of B2m
1) Confidence 0.66 Published 2008 Journal BMC Mol Biol Section Body Doc Link PMC2430208 Disease Relevance 0.47 Pain Relevance 0
In contrast, B2m transcript, which was identified as the most unstable gene by geNorm as well as by NormFinder, is 1.7-fold upregulated in the ACA group and twofold upregulated in the ACA with minocycline treatment group 4 days after treatment compared to the sham treated group.
Positive_regulation (upregulated) of B2m associated with myocardial infarction
2) Confidence 0.44 Published 2008 Journal BMC Mol Biol Section Body Doc Link PMC2430208 Disease Relevance 0.55 Pain Relevance 0
In contrast, B2m transcript, which was identified as the most unstable gene by geNorm as well as by NormFinder, is 1.7-fold upregulated in the ACA group and twofold upregulated in the ACA with minocycline treatment group 4 days after treatment compared to the sham treated group.
Positive_regulation (upregulated) of B2m associated with myocardial infarction
3) Confidence 0.44 Published 2008 Journal BMC Mol Biol Section Body Doc Link PMC2430208 Disease Relevance 0.56 Pain Relevance 0
B2m turned out to be the most variable candidate reference gene, being about 2-fold upregulated in the cardiac arrest treatment groups.


Positive_regulation (upregulated) of B2m associated with myocardial infarction
4) Confidence 0.38 Published 2008 Journal BMC Mol Biol Section Abstract Doc Link PMC2430208 Disease Relevance 0.75 Pain Relevance 0.12
Those continuously exposed to Cd had developed slight tubular damage, as evidenced by an increased urinary excretion of beta 2-microglobulin and beta-N-acetylglucosaminidase.
Positive_regulation (increased) of beta 2-microglobulin
5) Confidence 0.38 Published 1988 Journal Arch. Toxicol. Section Abstract Doc Link 3071304 Disease Relevance 0.22 Pain Relevance 0.85
By contrast, rats pretreated with acetaminophen for 2 months and exposed to Cd showed a marked increase in urinary excretion of albumin and beta 2-microglobulin, suggesting an interaction between both treatments.
Positive_regulation (increase) of beta 2-microglobulin associated with paracetamol
6) Confidence 0.38 Published 1988 Journal Arch. Toxicol. Section Abstract Doc Link 3071304 Disease Relevance 0.22 Pain Relevance 0.88

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox