INT347185

Context Info Confidence 0.12 First Reported 2011 Last Reported 2011 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.90 Pain Relevance 0

nucleolus (MYBL1) nucleus (MYBL1) DNA binding (MYBL1)

Anatomy Link Frequency B-cell 1 MYBL1 (Homo sapiens)

Pain Link Frequency Relevance Heat aspirin 7 5.00 alcohol 7 5.00 cINOD 4 5.00 cytokine 2 5.00 Shingles 2 5.00 COX2 1 5.00 Inflammation 1 5.00 vincristine 1 5.00

Disease Link Frequency Relevance Heat Sclerosis 9 91.28 Hodgkin's Disease 219 91.04 Cancer 27 84.48 Acquired Immune Deficiency Syndrome Or Hiv Infection 28 38.08 Malignant Neoplastic Disease 1 33.00 Anaemia 1 12.16 Epstein-barr Virus 85 5.00 Nicotine Addiction 45 5.00 Disease 17 5.00 Infection 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Before this finding, though, the origin of HRS was highly speculative because the cells rarely express typical B-cell markers such as BCR, CD19, CD20, A-myb, and Syk—thus an HRS cell's immunophenotype is not reflective of its origin.

Gene_expression (express) of A-myb in B-cell

1) Confidence 0.12 Published 2011 Journal Advances in Hematology Section Body Doc Link PMC2994062 Disease Relevance 0.90 Pain Relevance 0

General Comments

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