INT347369

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (RYBP, GSR) nucleoplasm (RYBP) mitochondrion (GSR)
small molecule metabolic process (GSR) intracellular (RYBP) DNA binding (RYBP)
RYBP (Homo sapiens)
GSR (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 83 100.00 Very High Very High Very High
Analgesic 1 26.96 Quite Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatotoxicity 9 87.88 High High
Stress 9 72.32 Quite High
Necrosis 2 62.88 Quite High
Toxicity 2 62.56 Quite High
Overdose 6 49.96 Quite Low
Injury 11 19.52 Low Low
Apoptosis 1 5.28 Low Low
Decapitation 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, the APAP-associated depletion of the intrahepatic GSH is accompanied by variable alterations in glutathione disulfide (GSSG) contents [11,12] and by reductions in the activities of the antioxidant enzymes glutathione reductase (GR) [13,14], ?
APAP Positive_regulation (enzymes) of GR associated with paracetamol
1) Confidence 0.01 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2994383 Disease Relevance 0.43 Pain Relevance 0.51

General Comments

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