INT34739

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Context Info
Confidence 0.35
First Reported 1988
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 17
Total Number 18
Disease Relevance 18.86
Pain Relevance 2.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
proximal 2
lungs 1
[[Del(7)Tyr<c-23DVT>-p]] (Mus musculus)
Pain Link Frequency Relevance Heat
cva 638 98.32 Very High Very High Very High
Pain 13 95.88 Very High Very High Very High
epidural 2 87.68 High High
Regional anesthesia 4 86.88 High High
anesthesia 12 84.84 Quite High
tolerance 4 61.12 Quite High
imagery 14 50.88 Quite High
abdominal pain 2 25.60 Quite Low
Lasting pain 1 25.00 Low Low
aspirin 10 8.64 Low Low
Disease Link Frequency Relevance Heat
Thrombosis 903 100.00 Very High Very High Very High
Deep Vein Thrombosis 420 100.00 Very High Very High Very High
Critical Illness 109 99.84 Very High Very High Very High
Thrombosis Related Under Development 67 99.40 Very High Very High Very High
Thrombophilia 7 98.84 Very High Very High Very High
Pulmonary Embolism 369 97.84 Very High Very High Very High
Frailty 25 97.12 Very High Very High Very High
Disease 4 96.88 Very High Very High Very High
Pain 12 95.88 Very High Very High Very High
Pressure And Volume Under Development 26 95.52 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although the exact cause of DVT is not known, venous thrombosis and its sequelae remain important clinical problems.
Positive_regulation (cause) of DVT associated with thrombosis related under development and thrombosis
1) Confidence 0.35 Published 1988 Journal Semin. Ultrasound CT MR Section Abstract Doc Link 3078972 Disease Relevance 0.69 Pain Relevance 0.05
Immobilisation following bone surgery significantly increases the risk of DVT, and prevention is a salient goal for nursing.
Positive_regulation (increases) of DVT associated with thrombosis
2) Confidence 0.35 Published 2007 Journal Br J Nurs Section Abstract Doc Link 17577167 Disease Relevance 0.89 Pain Relevance 0.14
The frequency of distal DVT (P<0.001), proximal DVT (P=0.018), and the combined rate of proximal DVT and PE (P=0.002) were significantly higher in the patients undergoing total knee replacement compared with the other groups of patients.
Positive_regulation (frequency) of DVT in proximal associated with cva and deep vein thrombosis
3) Confidence 0.14 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2800021 Disease Relevance 1.78 Pain Relevance 0.58
The frequency of distal DVT (P<0.001), proximal DVT (P=0.018), and the combined rate of proximal DVT and PE (P=0.002) were significantly higher in the patients undergoing total knee replacement compared with the other groups of patients.
Positive_regulation (frequency) of DVT in proximal associated with cva and deep vein thrombosis
4) Confidence 0.14 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2800021 Disease Relevance 1.80 Pain Relevance 0.59
Moreover, in Korea, the prevalence of DVT is increasing (Table 1).
Positive_regulation (increasing) of DVT associated with thrombosis
5) Confidence 0.08 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824863 Disease Relevance 1.17 Pain Relevance 0.03
Anomalies of the IVC are well described and recognised but are rare causes of DVT.
Positive_regulation (causes) of DVT associated with thrombosis
6) Confidence 0.05 Published 2008 Journal J Med Case Reports Section Body Doc Link PMC2262908 Disease Relevance 0.58 Pain Relevance 0
A review of the literature showed no previous systematic review has examined the evidence for an increase in the incidence of DVT amongst air travellers.
Spec (examined) Positive_regulation (increase) of DVT associated with thrombosis
7) Confidence 0.04 Published 2004 Journal BMC Cardiovasc Disord Section Body Doc Link PMC434500 Disease Relevance 0.98 Pain Relevance 0.13
If flight longer than 8 hours were associated with a very high risk of DVT (e.g.
Positive_regulation (risk) of DVT associated with thrombosis
8) Confidence 0.03 Published 2004 Journal BMC Cardiovasc Disord Section Body Doc Link PMC434500 Disease Relevance 0.24 Pain Relevance 0
Pooling these two studies revealed no evidence of an increase in the risk of DVT with prolonged air travel (odds ratio: 1.11, 95% CI: 0.64 to 1.94) (Figure 2).


Positive_regulation (increase) of DVT associated with thrombosis
9) Confidence 0.03 Published 2004 Journal BMC Cardiovasc Disord Section Body Doc Link PMC434500 Disease Relevance 1.01 Pain Relevance 0.06
Given the limited amount of evidence available, this review has insufficient power to confirm a statistically significant increase in risk of DVT associated with air travel, if such a risk exists.
Positive_regulation (increase) of DVT associated with thrombosis
10) Confidence 0.03 Published 2004 Journal BMC Cardiovasc Disord Section Body Doc Link PMC434500 Disease Relevance 0.53 Pain Relevance 0
Over the years, the majority of thromboprophylaxis trials have used DVT detected by sensitive screening methods such as venography as the primary efficacy outcome.
Positive_regulation (used) of DVT associated with thrombosis
11) Confidence 0.03 Published 2004 Journal Crit Care Section Body Doc Link PMC468908 Disease Relevance 0.84 Pain Relevance 0.03
We then surveyed respondents about the extent to which various factors influence their assessment of the clinical importance of DVT in critically ill patients.
Positive_regulation (importance) of DVT associated with critical illness and thrombosis
12) Confidence 0.03 Published 2004 Journal Crit Care Section Body Doc Link PMC468908 Disease Relevance 0.84 Pain Relevance 0.06
The pooled results across the four studies revealed evidence of a small but non-statistically significant increase in the risk of symptomatic DVT (odds ratio: 1.70, 95% CI: 0.89 to 3.22) associated with all forms of prolonged travel (Figure 3).


Positive_regulation (increase) of DVT associated with thrombosis
13) Confidence 0.03 Published 2004 Journal BMC Cardiovasc Disord Section Body Doc Link PMC434500 Disease Relevance 1.23 Pain Relevance 0.08
Patient factors considered to increase the clinical importance of a DVT, ranked according to the mean score, are shown in Table 1.
Positive_regulation (importance) of DVT associated with thrombosis
14) Confidence 0.03 Published 2004 Journal Crit Care Section Body Doc Link PMC468908 Disease Relevance 0.76 Pain Relevance 0.17
Furthermore, most critically ill patients are immobile, have central venous catheters in place and undergo numerous other procedures, all of which factors can increase the risk for DVT.
Positive_regulation (increase) of DVT associated with critical illness and thrombosis
15) Confidence 0.02 Published 2008 Journal Crit Care Section Body Doc Link PMC2447552 Disease Relevance 1.36 Pain Relevance 0
Although we did not find that conventional DVT risk factors such as thrombophilia or personal or family history of thrombosis conferred an increased risk for DVT, this may reflect the low prevalence of thrombophilia and a relatively underpowered regression analysis.
Positive_regulation (increased) of DVT associated with thrombophilia and thrombosis
16) Confidence 0.02 Published 2008 Journal Crit Care Section Body Doc Link PMC2447552 Disease Relevance 1.46 Pain Relevance 0
This last device catches blood clots before they reach the lungs but increases the risk of DVT.
Positive_regulation (increases) of DVT in lungs associated with deep vein thrombosis
17) Confidence 0.01 Published 2009 Journal PLoS Medicine Section Abstract Doc Link PMC2695771 Disease Relevance 1.72 Pain Relevance 0.41
Prophylactic placement of VCF in patients at high risk of VTE who cannot receive pharmacological prophylaxis is expensive, is associated with an increased risk of DVT, and should not be routinely performed.
Positive_regulation (increased) of DVT associated with cva and deep vein thrombosis
18) Confidence 0.01 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2695771 Disease Relevance 0.96 Pain Relevance 0.20

General Comments

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