INT347396

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.92
Pain Relevance 1.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (RYBP, Sdcbp) nucleoplasm (RYBP) plasma membrane (Sdcbp)
nucleus (RYBP) intracellular (RYBP) DNA binding (RYBP)
Anatomy Link Frequency
plasma 3
liver 1
RYBP (Homo sapiens)
Sdcbp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 166 100.00 Very High Very High Very High
Potency 2 62.64 Quite High
Analgesic 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatotoxicity 18 99.48 Very High Very High Very High
Decapitation 4 79.84 Quite High
Injury 22 68.80 Quite High
Overdose 12 51.72 Quite High
Stress 18 5.00 Very Low Very Low Very Low
Toxicity 4 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By itself, APAP increased MDA formation and had a significant lowering influence on the levels of GSH and GSSG, the GSH/GSSH ratio, and the activities of GR, GST and GCS both in the plasma and liver.
APAP Positive_regulation (increased) of MDA Binding (formation) of in plasma associated with paracetamol
1) Confidence 0.00 Published 2010 Journal J Biomed Sci Section Abstract Doc Link PMC2994383 Disease Relevance 0.46 Pain Relevance 0.83
By itself, APAP increased MDA formation and had a significant lowering influence on the levels of GSH and GSSG, the GSH/GSSH ratio, and the activities of GR, GST and GCS both in the plasma and liver.
APAP Positive_regulation (increased) of MDA in liver Binding (formation) of in plasma associated with paracetamol
2) Confidence 0.00 Published 2010 Journal J Biomed Sci Section Abstract Doc Link PMC2994383 Disease Relevance 0.46 Pain Relevance 0.83

General Comments

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