INT347397

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.22
Pain Relevance 1.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (RYBP, Sdcbp) nucleoplasm (RYBP) plasma membrane (Sdcbp)
nucleus (RYBP) intracellular (RYBP) DNA binding (RYBP)
Anatomy Link Frequency
plasma 2
RYBP (Homo sapiens)
Sdcbp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 166 100.00 Very High Very High Very High
Analgesic 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 18 80.00 Quite High
Injury 22 77.92 Quite High
Hepatotoxicity 18 50.00 Quite Low
Overdose 12 5.00 Very Low Very Low Very Low
Toxicity 4 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Decapitation 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
From the results presented in Figure 8, it is evident that APAP promoted LPO by increasing the levels of MDA both in the liver (134%) and plasma (by 217%) above control values (p<0.001 for both).
APAP Positive_regulation (increasing) of MDA in plasma associated with paracetamol
1) Confidence 0.00 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2994383 Disease Relevance 0 Pain Relevance 0.78
Likewise, the increase in the plasma MDA induced by APAP was reduced to 32% by NAC (p<0.01), to 36% by HYTAU (p<0.01), and to 90% by TAU (p<0.001) relative to the control value (Figure 8).


APAP Positive_regulation (induced) of MDA in plasma associated with paracetamol
2) Confidence 0.00 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2994383 Disease Relevance 0.22 Pain Relevance 0.78

General Comments

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