INT347526

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Context Info
Confidence 0.62
First Reported 2010
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.65
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Nrp2) cell adhesion (Nrp2) plasma membrane (Nrp2)
Anatomy Link Frequency
lymph nodes 2
corneas 2
Nrp2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 12 73.28 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 6 97.88 Very High Very High Very High
Organ Transplantation 12 77.80 Quite High
Adhesions 2 77.28 Quite High
INFLAMMATION 12 73.28 Quite High
Disease 8 67.24 Quite High
Aids-related Complex 4 60.00 Quite High
Metastasis 4 39.16 Quite Low
Cancer 10 37.84 Quite Low
Corneal Neovascularization 6 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To determine the effect of reduced NP2 expression on cell infiltration associated with corneal suture injury in recipient beds immediately before transplantation, we next examined CD11 antigen-like family member B (CD11b)-positive macrophage infiltration into inflamed corneas in mice treated with NP2-amiR.
Spec (determine) Regulation (effect) of Gene_expression (expression) of NP2 in corneas associated with injury
1) Confidence 0.62 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2994732 Disease Relevance 0.32 Pain Relevance 0.04
These data demonstrate that decreasing NP2 expression has no direct effect on corneal macrophages trafficking to regional lymph nodes, and further confirm the selective effect of NP2 knockdown in the inflamed cornea.
Neg (no) Regulation (effect) of Gene_expression (expression) of NP2 in lymph nodes
2) Confidence 0.45 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2994732 Disease Relevance 0.33 Pain Relevance 0.03

General Comments

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