INT34769

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Context Info
Confidence 0.19
First Reported 1986
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.39
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (AGT) small molecule metabolic process (AGT) aging (AGT)
extracellular region (AGT) extracellular matrix organization (AGT) cell-cell signaling (AGT)
Anatomy Link Frequency
blood 2
PGE2 2
AGT (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 14 97.56 Very High Very High Very High
Inflammation 2 93.88 High High
metalloproteinase 1 86.60 High High
Potency 2 76.32 Quite High
cytokine 1 74.52 Quite High
fibrosis 1 67.84 Quite High
Neuropeptide 238 65.68 Quite High
Analgesic 1 30.48 Quite Low
beta blocker 3 29.16 Quite Low
Inflammatory response 1 8.16 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 93.88 High High
Cicatrix 3 92.64 High High
Infarction 21 91.36 High High
Pressure And Volume Under Development 3 84.12 Quite High
Pre-eclampsia 5 78.16 Quite High
Disease 20 69.28 Quite High
Fibrosis 1 67.84 Quite High
Coronary Heart Disease 5 65.04 Quite High
Diabetes Mellitus 4 54.16 Quite High
Intrauterine Growth Retardation 1 53.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
They also express ACE activity and provide a local source of angiotensin II production that is independent of systemic angiotensin II [22].
Neg (independent) Regulation (independent) of Gene_expression (production) of angiotensin II
1) Confidence 0.19 Published 2001 Journal Curr Control Trials Cardiovasc Med Section Body Doc Link PMC59642 Disease Relevance 0.78 Pain Relevance 0.20
It is assumed that PGE2/PGI2 production and the renin angiotensin production influence each other physiologically.
Regulation (influence) of Gene_expression (production) of angiotensin in PGE2
2) Confidence 0.16 Published 1986 Journal Geburtshilfe Frauenheilkd Section Abstract Doc Link 3082707 Disease Relevance 0.48 Pain Relevance 0
The effects of an inhibitor of angiotensin-converting enzyme (ACE) on the profile of these vasoactive peptides illustrated that the drug affects not only its ACE target for angiotensin production but also results in prominent alteration of the profiles of bradykinin and related peptides that regulate blood pressure (Fig. 5) (29).
Regulation (affects) of Gene_expression (production) of angiotensin in blood associated with bradykinin
3) Confidence 0.02 Published 2010 Journal AAPS J Section Body Doc Link PMC2976990 Disease Relevance 0.14 Pain Relevance 0.47

General Comments

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