INT347696

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ZBTB16) intracellular (ZBTB16) DNA binding (ZBTB16)
Anatomy Link Frequency
patterning 1
ZBTB16 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 30 50.00 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
pregabalin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemangiosarcoma 139 99.84 Very High Very High Very High
Leukemia 6 98.46 Very High Very High Very High
Myeloid Sarcoma 1 92.20 High High
Cancer 85 82.64 Quite High
INFLAMMATION 30 50.00 Quite Low
Adhesions 7 49.00 Quite Low
Chronic Myeloid Leukemia 1 44.32 Quite Low
Epstein-barr Virus 1 41.68 Quite Low
Malignant Neoplastic Disease 25 5.00 Very Low Very Low Very Low
Hematoma 22 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This interpretation is supported by the general enrichment of genes overexpressed in dendritic cells and in leukemia, as well as by enrichment of the patterning gene HOXA10 and by the specific downregulation of PLZF in hemangiosarcomas; both of which are involved in hematopoietic differentiation [45,69].
Negative_regulation (downregulation) of PLZF in patterning associated with leukemia and hemangiosarcoma
1) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2994824 Disease Relevance 1.21 Pain Relevance 0

General Comments

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