INT347901

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.45 Pain Relevance 0.42

DNA binding (Nfkb1, Gtf3a) nucleus (Nfkb1, Gtf3a) mitochondrion (Nfkb1) intracellular (Gtf3a) protein complex (Nfkb1) cytoplasm (Nfkb1)

Nfkb1 (Mus musculus) Gtf3a (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 34 98.68 cytokine 35 91.28 chemokine 5 32.64 Inflammatory mediators 2 31.16 dexamethasone 4 5.00 cINOD 2 5.00 Inflammatory response 2 5.00 anesthesia 1 5.00 Arthritis 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 40 98.68 Cancer 5 5.00 Disease 4 5.00 Toxicity 2 5.00 Necrosis 2 5.00 Arthritis 1 5.00 Apoptosis 1 5.00 Increased Venous Pressure Under Development 1 5.00 Skin Cancer 1 5.00 Peripheral Arterial Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The inducible transcription factor NF-kB is responsible for the regulation of a plethora of genes involved in carcinogenesis and inflammation [4].

Positive_regulation (inducible) of NF-kB Regulation (responsible) of Transcription (transcription) of factor associated with inflammation

1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2995738 Disease Relevance 0.45 Pain Relevance 0.42

General Comments

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