INT34791

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.75
First Reported 1986
Last Reported 2006
Negated 0
Speculated 1
Reported most in Title
Documents 5
Total Number 6
Disease Relevance 0.54
Pain Relevance 1.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (B3GAT2)
Anatomy Link Frequency
liver 2
2B7 1
intestine 1
B3GAT2 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 6 99.40 Very High Very High Very High
Morphine 5 99.14 Very High Very High Very High
cINOD 9 97.64 Very High Very High Very High
Pain 1 94.80 High High
Arthritis 1 94.44 High High
Catecholamine 2 94.16 High High
Paracetamol 7 91.92 High High
Inflammation 1 89.04 High High
Bile 1 76.44 Quite High
Buprenorphine 3 44.40 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 96.40 Very High Very High Very High
Pain 1 94.80 High High
Arthritis 1 94.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Stably expressed human and rat phenol UDP-glucuronosyltransferases (UGTs) of the UGT1 complex (HlugP1, HlugP4 and 3-methylcholanthrene-inducible rat UGT1A1, the latter considered to be an orthologous enzyme to HlugP1) have been used to investigate the role of UGTs in paracetamol glucuronidation.
Gene_expression (expressed) of UDP-glucuronosyltransferases associated with paracetamol
1) Confidence 0.75 Published 1993 Journal Biochem. Pharmacol. Section Abstract Doc Link 8494539 Disease Relevance 0 Pain Relevance 0.29
Glucuronidation of catechol estrogens by expressed human UDP-glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7.
Gene_expression (expressed) of UDP-glucuronosyltransferases in 2B7
2) Confidence 0.75 Published 1998 Journal Toxicol. Sci. Section Title Doc Link 9848110 Disease Relevance 0 Pain Relevance 0.14
Glucuronidation of the aspirin metabolite salicylic acid by expressed UDP-glucuronosyltransferases and human liver microsomes.
Gene_expression (expressed) of UDP-glucuronosyltransferases in liver associated with aspirin
3) Confidence 0.75 Published 2006 Journal Drug Metab. Dispos. Section Title Doc Link 16258079 Disease Relevance 0.37 Pain Relevance 0.53
In this report, the contribution of UDP-glucuronosyltransferases (UGTs) in the human gastrointestinal (GI) tract from five donors to the glucuronidation of the NSAIDs, RS-ketoprofen, S-naproxen, RS- and S-etodolac, was investigated.
Spec (investigated) Gene_expression (contribution) of UDP-glucuronosyltransferases associated with cinod
4) Confidence 0.65 Published 2004 Journal Biochim. Biophys. Acta Section Abstract Doc Link 15535975 Disease Relevance 0.17 Pain Relevance 0.59
Presystemic glucuronidation of morphine in humans and rhesus monkeys: subcellular distribution of the UDP-glucuronyltransferase in the liver and intestine.
Gene_expression (distribution) of UDP-glucuronyltransferase in liver associated with morphine
5) Confidence 0.50 Published 1986 Journal Xenobiotica Section Title Doc Link 3083607 Disease Relevance 0 Pain Relevance 0.19
Presystemic glucuronidation of morphine in humans and rhesus monkeys: subcellular distribution of the UDP-glucuronyltransferase in the liver and intestine.
Gene_expression (distribution) of UDP-glucuronyltransferase in intestine associated with morphine
6) Confidence 0.17 Published 1986 Journal Xenobiotica Section Title Doc Link 3083607 Disease Relevance 0 Pain Relevance 0.19

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox