INT347962

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cpox, Nos1) cytoplasm (Cpox, Nos1) oxidoreductase activity (Cpox, Nos1)
aging (Nos1) enzyme binding (Nos1) cytosol (Nos1)
Anatomy Link Frequency
neuronal 2
Cpox (Rattus norvegicus)
Nos1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuronal nitric oxide synthase 1 100.00 Very High Very High Very High
Migraine 11 97.76 Very High Very High Very High
Pain 3 87.16 High High
headache 34 83.12 Quite High
algogenic 1 76.72 Quite High
cINOD 15 73.36 Quite High
Calcitonin gene-related peptide 33 57.72 Quite High
antagonist 1 50.76 Quite High
Cluster headache 2 9.52 Low Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 35 97.76 Very High Very High Very High
Increased Venous Pressure Under Development 46 88.84 High High
Pain 3 87.16 High High
Paroxysmal Hemicrania 6 67.08 Quite High
Trigeminal Autonomic Cephalalgias 1 45.40 Quite Low
Disease 1 21.68 Low Low
Alzheimer's Dementia 2 10.72 Low Low
Cluster Headache 2 9.52 Low Low
Nociception 3 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In earlier experiments it was also shown that COX-2 inhibition but not COX-1 inhibition can decrease the level of neuronal nitric oxide synthase induction as induced by NO donors [37].
COX Negative_regulation (decrease) of Positive_regulation (induction) of neuronal nitric oxide synthase in neuronal associated with neuronal nitric oxide synthase
1) Confidence 0.02 Published 2010 Journal J Headache Pain Section Body Doc Link PMC2995862 Disease Relevance 0.59 Pain Relevance 0.67

General Comments

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