INT348012

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.93
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Samsn1) transport (Vps54) growth (Vps54)
nucleus (Samsn1)
Samsn1 (Rattus norvegicus)
Vps54 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 1 91.84 High High
cytokine 10 89.84 High High
Inflammation 23 53.92 Quite High
fibrosis 4 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 47 100.00 Very High Very High Very High
Nash(non-alcoholic Steatohepatitis) 9 100.00 Very High Very High Very High
Insulin Resistance 2 98.60 Very High Very High Very High
Fatty Liver 3 97.60 Very High Very High Very High
Obesity 3 97.60 Very High Very High Very High
INFLAMMATION 23 91.84 High High
Hepatitis C Virus Infection 8 85.40 High High
Injury 4 74.28 Quite High
Hepatitis B Virus Infection 8 69.32 Quite High
Cancer 40 66.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several mechanisms have been proposed to explain how NASH increases HCC risk, including the prevalence of insulin resistance among obese individuals, which results in elevated circulating concentrations of insulin and insulin-like growth factor 1 (IGF-1) [7] and a low-grade inflammatory response with elevated production of cytokines, such as TNF and IL-6 [8].
NASH Positive_regulation (increases) of HCC associated with nash(non-alcoholic steatohepatitis), inflammatory response, obesity, hepatocellular cancer, insulin resistance and cytokine
1) Confidence 0.00 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2995932 Disease Relevance 1.93 Pain Relevance 0.15

General Comments

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