INT348016

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.09
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mapk8, Mapk8ip3) kinase activity (Mapk8, Mapk8ip3) mitochondrion (Mapk8)
Golgi apparatus (Mapk8ip3) cytosol (Mapk8) signal transduction (Mapk8)
Mapk8 (Mus musculus)
Mapk8ip3 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 4 97.60 Very High Very High Very High
fibrosis 8 67.24 Quite High
Inflammation 46 65.36 Quite High
metalloproteinase 6 12.84 Low Low
cytokine 20 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 94 97.76 Very High Very High Very High
Hepatitis 14 96.60 Very High Very High Very High
Death 16 76.64 Quite High
Cancer 80 69.56 Quite High
Fibrosis 4 67.24 Quite High
INFLAMMATION 46 66.08 Quite High
Hepatitis C Virus Infection 16 54.68 Quite High
Hepatitis B Virus Infection 16 54.28 Quite High
Targeted Disruption 26 45.12 Quite Low
Apoptosis 22 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a mouse model, the cell-permeable JIP peptide, which interferes with the interaction between JIP and JNK to inhibit JNK activity, suppresses chemically induced HCC [59].


JNK Binding (interaction) of JIP associated with hepatocellular cancer
1) Confidence 0.04 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2995932 Disease Relevance 1.03 Pain Relevance 0.16
In a mouse model, the cell-permeable JIP peptide, which interferes with the interaction between JIP and JNK to inhibit JNK activity, suppresses chemically induced HCC [59].


JNK Binding (interaction) of JIP associated with hepatocellular cancer
2) Confidence 0.04 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2995932 Disease Relevance 1.05 Pain Relevance 0.16

General Comments

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