INT348030

Context Info Confidence 0.17 First Reported 2010 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.95 Pain Relevance 0.06

cytosol (Mapk8) signal transduction (Mapk8) mitochondrion (Mapk8) growth (Re) nucleus (Mapk8) kinase activity (Mapk8)

Mapk8 (Mus musculus) Re (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 23 59.80 chemokine 1 56.20 cytokine 10 5.00 fibrosis 4 5.00 metalloproteinase 3 5.00 Paracetamol 2 5.00 Inflammatory response 1 5.00 alcohol 1 5.00

Disease Link Frequency Relevance Heat Hepatocellular Cancer 47 97.60 Liver Cancer 3 87.24 Cancer 40 78.84 Hepatitis C Virus Infection 8 75.96 Hepatitis B Virus Infection 8 75.64 INFLAMMATION 23 59.80 Metastasis 4 18.68 Apoptosis 11 17.08 Targeted Disruption 13 5.00 Nash(non-alcoholic Steatohepatitis) 9 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Additionally, to determine the role of JNK1 in DEN-induced hepatocarcinogenesis, wild-type and Jnk1-deficient mice were injected with DEN.

JNK1 Spec (determine) Regulation (role) of DEN-induced

1) Confidence 0.17 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2995932 Disease Relevance 0.95 Pain Relevance 0.06

General Comments

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