INT348041

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.41
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Irf3) DNA binding (Irf3) cytoplasm (Irf3)
IFNA1 (Homo sapiens)
Irf3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 10 95.28 Very High Very High Very High
Inflammation 23 92.16 High High
alcohol 1 82.16 Quite High
fibrosis 4 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatitis C Virus Infection 8 92.52 High High
INFLAMMATION 23 92.16 High High
Hepatitis B Virus Infection 8 88.16 High High
Targeted Disruption 13 79.96 Quite High
Hepatocellular Cancer 47 77.04 Quite High
Nash(non-alcoholic Steatohepatitis) 9 75.72 Quite High
Alcoholic Liver Diseases 2 75.32 Quite High
Liver Disease 4 70.92 Quite High
Obesity 3 54.32 Quite High
Disease 1 32.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The NS3 protein interacts directly with TBK1, resulting in decreased TBK1-IRF3 interaction and inhibition of IRF3 and IFN transcription.
IFN Binding (interaction) of IRF3
1) Confidence 0.02 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2995932 Disease Relevance 1.41 Pain Relevance 0.20

General Comments

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