INT348043

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.04
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mapk8, Mapk8ip3) kinase activity (Mapk8, Mapk8ip3) transport (Vps54)
mitochondrion (Mapk8) Golgi apparatus (Mapk8ip3) cytosol (Mapk8)
Mapk8 (Mus musculus)
Mapk8ip3 (Mus musculus)
Vps54 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 2 96.04 Very High Very High Very High
fibrosis 4 65.68 Quite High
Inflammation 23 63.80 Quite High
metalloproteinase 3 11.28 Low Low
cytokine 10 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 47 100.00 Very High Very High Very High
Hepatitis 7 95.04 Very High Very High Very High
Death 8 75.08 Quite High
Cancer 40 68.00 Quite High
Fibrosis 2 65.68 Quite High
INFLAMMATION 23 64.52 Quite High
Hepatitis C Virus Infection 8 53.12 Quite High
Hepatitis B Virus Infection 8 52.72 Quite High
Targeted Disruption 13 43.56 Quite Low
Apoptosis 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a mouse model, the cell-permeable JIP peptide, which interferes with the interaction between JIP and JNK to inhibit JNK activity, suppresses chemically induced HCC [59].


JNK Binding (interaction) of JIP Negative_regulation (suppresses) of Positive_regulation (induced) of HCC associated with hepatocellular cancer
1) Confidence 0.00 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2995932 Disease Relevance 1.04 Pain Relevance 0.16

General Comments

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