INT34809

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Context Info
Confidence 0.15
First Reported 1986
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 36
Total Number 37
Disease Relevance 15.70
Pain Relevance 3.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
hearts 3
neurons 2
skin 2
T cells 2
brain 1
Ec (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 28 99.24 Very High Very High Very High
Inflammation 151 98.56 Very High Very High Very High
tolerance 468 97.68 Very High Very High Very High
Dorsal horn 5 94.12 High High
GABAergic 17 92.00 High High
Enkephalin 5 90.36 High High
amygdala 1 90.00 High High
rheumatoid arthritis 80 86.04 High High
analgesia 7 81.76 Quite High
Dorsal horn neuron 1 80.76 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 1677 100.00 Very High Very High Very High
Varicose Veins 334 100.00 Very High Very High Very High
Infection 275 99.88 Very High Very High Very High
Hypoxia 1 99.08 Very High Very High Very High
INFLAMMATION 154 98.56 Very High Very High Very High
Anaemia 8 97.24 Very High Very High Very High
Adhesions 3 96.24 Very High Very High Very High
Congenital Anomalies 58 95.60 Very High Very High Very High
Rupture 14 94.96 High High
Hemorrhage 162 93.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The vascular EC within the donor hearts continued to express ?
Gene_expression (express) of EC in hearts
1) Confidence 0.15 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.41 Pain Relevance 0.04
Unlike some cell types such as neurons, which express almost no MHC proteins, murine and human EC express easily detectable levels of MHC class I proteins in vivo [29,30].
Gene_expression (express) of EC in neurons
2) Confidence 0.15 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.09 Pain Relevance 0.16
Dermal EC also continued to express ?
Gene_expression (express) of EC
3) Confidence 0.15 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.40 Pain Relevance 0
Dermal EC also continued to express ?
Gene_expression (continued) of EC
4) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.40 Pain Relevance 0
-gal expressed by EC is ignored by the immune system, is not supported by the findings that skin containing ?
Gene_expression (expressed) of EC in immune system
5) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.22 Pain Relevance 0.12
-gal expressed by heart and or brain EC is not ignored, but is presented, albeit in a manner that does not render the host completely unresponsive.
Gene_expression (expressed) of EC in brain
6) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.16 Pain Relevance 0.10
-gal expressing EC triggered an antigen-specific immune response when transplanted onto wild type, but not TIE2-lacZ mice (Figure 6).
Gene_expression (expressing) of EC
7) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.22 Pain Relevance 0.11
The immunized transgenic mice remained healthy, their EC continued to express ?
Gene_expression (express) of EC associated with targeted disruption
8) Confidence 0.13 Published 2004 Journal BMC Immunol Section Abstract Doc Link PMC394319 Disease Relevance 0.76 Pain Relevance 0
The immunized transgenic mice remained healthy, their EC continued to express ?
Gene_expression (continued) of EC associated with targeted disruption
9) Confidence 0.13 Published 2004 Journal BMC Immunol Section Abstract Doc Link PMC394319 Disease Relevance 0.76 Pain Relevance 0
Cardiac EC expressed equivalent, easily detectable amounts of ?
Gene_expression (expressed) of EC
10) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.46 Pain Relevance 0
-gal peptides presented on EC.
Gene_expression (presented) of EC
11) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.97 Pain Relevance 0
EC continue to express ?
Gene_expression (express) of EC
12) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 1.39 Pain Relevance 0
The EC in these transgenic mice also express significant amounts of ?
Gene_expression (express) of EC associated with targeted disruption
13) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.10 Pain Relevance 0.18
The vascular EC within the donor hearts continued to express ?
Gene_expression (continued) of EC in hearts
14) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.41 Pain Relevance 0.04
EC continue to express ?
Gene_expression (continue) of EC
15) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 1.39 Pain Relevance 0
-gal+ EC in TIE2-lacZ skin grafts (Figure 6B) strongly suggests that specific lymphocytes directly recognize and are rendered unresponsive by resting, endogenous, ?
Gene_expression (gal+) of EC in skin
16) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.15 Pain Relevance 0.09
-gal expression by EC within the skin grafts was analyzed by X-gal staining.
Spec (analyzed) Gene_expression (expression) of EC in skin
17) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.12 Pain Relevance 0
-gal, despite generating specific antisera and T cells, because they do not appear to injure their own EC that express the antigen.
Gene_expression (express) of EC in T cells
18) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.18 Pain Relevance 0.17
-gal expression patterns and concluded that in post-embryonic mice, vascular EC alone expressed ?
Gene_expression (expression) of EC
19) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.41 Pain Relevance 0.16
However, any circulation would expose T cells to antigens expressed by vascular EC.
Gene_expression (expressed) of EC in T cells
20) Confidence 0.13 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0.08 Pain Relevance 0.19

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