INT348149

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.94
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Thbs1) cytoplasm (Thbs1)
Anatomy Link Frequency
astrocytes 4
Thbs1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Gabapentin 2 73.92 Quite High
cytokine 2 54.72 Quite High
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 242 98.92 Very High Very High Very High
Stress 8 83.64 Quite High
Parkinson's Disease 8 82.80 Quite High
Apoptosis 2 69.44 Quite High
Generaliased Trisomy 2 67.12 Quite High
Cancer 2 67.08 Quite High
Congenital Anomalies 8 23.72 Low Low
Cognitive Disorder 8 20.68 Low Low
Stroke 4 10.48 Low Low
Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antioxidants and mitochondrial cofactors have no effect on TSP-1 expression and secretory deficits in DS astrocytes
Neg (no) Regulation (effect) of Gene_expression (expression) of TSP-1 in astrocytes associated with syndrome
1) Confidence 0.31 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2996288 Disease Relevance 1.01 Pain Relevance 0
One possibility is that mechanism(s) regulating TSP-1 expression such as activation of purinergic receptors [97], muscarinic receptors [74], or nitric oxide-mediated signaling [89], [98] could be altered in DS astrocytes.
Regulation (regulating) of Gene_expression (expression) of TSP-1 in astrocytes associated with syndrome
2) Confidence 0.14 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2996288 Disease Relevance 0.93 Pain Relevance 0.10

General Comments

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