INT348150

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.06
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Thbs1) cytoplasm (Thbs1)
Anatomy Link Frequency
astrocytes 1
neurite 1
Thbs1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Gabapentin 3 98.72 Very High Very High Very High
imagery 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 363 98.68 Very High Very High Very High
Cancer 3 94.92 High High
Parkinson's Disease 12 82.16 Quite High
Stress 12 78.96 Quite High
Congenital Anomalies 12 73.16 Quite High
Cognitive Disorder 12 70.12 Quite High
Stroke 6 59.92 Quite High
Generaliased Trisomy 3 10.72 Low Low
Disease 12 5.00 Very Low Very Low Very Low
Intellectual Impairment 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TSP-1 can bind and activate integrin receptors to mediate neurite outgrowth [28], and some studies suggest that TSP-1 can reorganize the actin cytoskeleton through stimulation of phosphoinositide 3-kinase (PI3-K) [87].
TSP-1 Binding (bind) of in neurite
1) Confidence 0.24 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2996288 Disease Relevance 0.56 Pain Relevance 0.06
TSP-1 regulates spine morphology and prevents spine alterations in neurons grown on top of DS astrocytes
TSP-1 Binding (prevents) of in astrocytes associated with syndrome
2) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2996288 Disease Relevance 0.83 Pain Relevance 0
Recent studies show that TSP-1 can interact with the ?
TSP-1 Binding (interact) of
3) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2996288 Disease Relevance 0.67 Pain Relevance 0.10

General Comments

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