INT34817

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Context Info
Confidence 0.31
First Reported 1986
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.16
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (TNIP1) intracellular (TNIP1) translation (TNIP1)
cytoplasm (TNIP1)
TNIP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 4 99.92 Very High Very High Very High
qutenza 2 99.92 Very High Very High Very High
bradykinin 1 99.36 Very High Very High Very High
Nicotine 44 87.16 High High
agonist 34 74.08 Quite High
Pain 3 25.00 Low Low
addiction 14 6.96 Low Low
Inflammation 9 5.00 Very Low Very Low Very Low
gABA 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Blister 3 86.48 High High
Toxicity 12 5.00 Very Low Very Low Very Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Cognitive Disorder 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Granuloma 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interactions between CS, CR, VAN, capsaicin and bradykinin were investigated to discover any common pathways of irritant activity.
VAN Binding (Interactions) of associated with qutenza and bradykinin
1) Confidence 0.31 Published 1986 Journal Pain Section Abstract Doc Link 3088535 Disease Relevance 0.16 Pain Relevance 0.25
As a result, the binding energy function has an accuracy of 2.5 kcal/mol, but does not account for potential Van der Waals clashes.
Van Neg (not) Binding (account) of
2) Confidence 0.08 Published 2002 Journal BMC Struct Biol Section Body Doc Link PMC65631 Disease Relevance 0 Pain Relevance 0.10
The binding energy function, previously validated against a diversified benchmark [20], includes a hydrophobic term, an electrostatic term, and an entropic term, but does not include Van der Waals energy, since this term is too noisy; Van der Waals interactions are supposed to be proportional to the interface of the interacting molecules, and incorporated into the surface (hydrophobic) term (see Materials and Methods).
Van Binding (interactions) of
3) Confidence 0.08 Published 2002 Journal BMC Struct Biol Section Body Doc Link PMC65631 Disease Relevance 0 Pain Relevance 0.14
Note that molecular dynamics simulation shows the insertion of long polymeric molecules inside carbon nanotubes in the result of Van der Waals interaction (Wei and Srivastava 2003).
Van Binding (interaction) of
4) Confidence 0.02 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2676659 Disease Relevance 0 Pain Relevance 0

General Comments

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