INT348398

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.88
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (LPA) small molecule metabolic process (LPA) cytoplasm (Pik3cb)
lipid metabolic process (LPA) cytosol (Pik3cb) peptidase activity (LPA)
LPA (Homo sapiens)
Pik3cb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 13 99.60 Very High Very High Very High
Stimulus evoked pain 1 97.32 Very High Very High Very High
qutenza 2 90.80 High High
Inflammation 2 89.40 High High
Hyperalgesia 5 88.96 High High
peripheral neuropathy 1 88.72 High High
Antinociceptive 2 83.56 Quite High
Central nervous system 3 75.16 Quite High
central sensitization 1 72.24 Quite High
substance P 3 71.44 Quite High
Disease Link Frequency Relevance Heat
Pain 14 99.60 Very High Very High Very High
Hypersensitivity 1 97.12 Very High Very High Very High
INFLAMMATION 3 89.40 High High
Hyperalgesia 6 88.96 High High
Peripheral Neuropathy 1 88.72 High High
Nociception 3 73.72 Quite High
Neuropathic Pain 3 49.44 Quite Low
Heart Disease 1 45.84 Quite Low
Hypertension 1 45.12 Quite Low
Nervous System Injury 1 42.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LPA-induced activation of phosphatidylinositol–3 kinase (PI3K) has been suggested to play an essential role in the induction of pain hypersensitivity [41].
LPA Positive_regulation (activation) of PI3K associated with hypersensitivity and stimulus evoked pain
1) Confidence 0.04 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2996792 Disease Relevance 0.88 Pain Relevance 1.14

General Comments

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