INT348403

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (FDPS, FDPS, Fdps) nucleolus (FDPS, FDPS, Fdps) nucleus (FDPS, FDPS, Fdps)
cytoplasm (FDPS, FDPS, Fdps) cytosol (FDPS, FDPS) small molecule metabolic process (FDPS, FDPS)
FDPS (Homo sapiens)
FDPS (Homo sapiens)
Fdps (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 3 97.24 Very High Very High Very High
Antinociceptive 2 96.24 Very High Very High Very High
central sensitization 1 94.32 High High
Hyperalgesia 5 89.36 High High
peripheral neuropathy 1 86.40 High High
Inflammation 2 84.32 Quite High
antinociception 1 82.40 Quite High
Pain 13 81.52 Quite High
cytokine 2 73.64 Quite High
bradykinin 2 73.08 Quite High
Disease Link Frequency Relevance Heat
Nociception 3 95.80 Very High Very High Very High
Hyperalgesia 6 89.36 High High
Peripheral Neuropathy 1 86.40 High High
INFLAMMATION 3 84.32 Quite High
Pain 14 81.52 Quite High
Heart Disease 1 67.92 Quite High
Hypertension 1 67.20 Quite High
Urological Neuroanatomy 9 55.28 Quite High
Hypersensitivity 1 51.52 Quite High
Stress 2 13.20 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Along with HMG CoA reductase, bisphosphonate is also known to decrease FPP levels primarily by inhibiting farnesyl diphosphate synthase (FPPS) [34].
FPPS Negative_regulation (inhibiting) of farnesyl diphosphate synthase Negative_regulation (decrease) of FPP
1) Confidence 0.03 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2996792 Disease Relevance 0.79 Pain Relevance 0.71

General Comments

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