INT348534

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ELMO1, RAC1) plasma membrane (ELMO1, RAC1) enzyme binding (RAC1)
GTPase activity (RAC1) cytoplasm (ELMO1) cell adhesion (RAC1)
Anatomy Link Frequency
epithelial cells 1
ELMO1 (Homo sapiens)
RAC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 26 96.68 Very High Very High Very High
Apoptosis 136 91.96 High High
Cancer 8 74.76 Quite High
Retinoblastoma 3 74.52 Quite High
Death 6 5.00 Very Low Very Low Very Low
Repression 4 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Shigella Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Shigella effector IpgB1 binds to ELMO1 to stimulate Rac1 activity, which induces membrane ruffling during invasion of epithelial cells.
ELMO1 Positive_regulation (stimulate) of Rac1 in epithelial cells
1) Confidence 0.02 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2996966 Disease Relevance 0.70 Pain Relevance 0

General Comments

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