INT348535

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.30 Pain Relevance 0

cytosol (CASP10, CASP3) peptidase activity (CASP10, CASP3) plasma membrane (CASP10, CASP3) nucleoplasm (CASP3) mitochondrion (CASP3) cytoplasm (CASP3)

CASP10 (Homo sapiens) CASP3 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 3 5.00 cytokine 2 5.00 alcohol 1 5.00 abdominal pain 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 136 94.56 Shigella Infection 3 83.12 Repression 4 56.48 Infection 26 49.12 Cancer 8 5.00 Death 6 5.00 Sprains And Strains 4 5.00 Retinoblastoma 3 5.00 Necrosis 3 5.00 INFLAMMATION 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In addition, caspase-10 is activated after cytochrome c release to amplify caspase-9 and caspase-3 activation in the presence of etoposide.

caspase-10 Positive_regulation (activation) of caspase-3

1) Confidence 0.03 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2996966 Disease Relevance 0.30 Pain Relevance 0

General Comments

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