INT348536

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.55
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TP63, CASP9) nucleus (TP63, CASP9) nucleoplasm (TP63)
anatomical structure formation involved in morphogenesis (TP63) Golgi apparatus (TP63) intracellular (CASP9)
TP63 (Homo sapiens)
CASP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 3 22.16 Low Low
cytokine 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 136 96.24 Very High Very High Very High
Cancer 8 79.00 Quite High
Death 6 54.00 Quite High
Repression 4 44.44 Quite Low
INFLAMMATION 3 22.16 Low Low
Infection 26 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Retinoblastoma 3 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Shigella Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The induction of TP63 most likely lead to the increased expression of BAX, APAF1, and caspase-9 seen in WTSTS cells.
Positive_regulation (induction) of TP63 Positive_regulation (lead) of Gene_expression (expression) of caspase-9
1) Confidence 0.02 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2996966 Disease Relevance 0.55 Pain Relevance 0

General Comments

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