INT348592

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (HDAC1, PPARG) enzyme binding (HDAC1, PPARG) cytoplasm (HDAC1, PPARG)
cytosol (HDAC1, PPARG) nucleus (HDAC1, PPARG) DNA binding (PPARG)
HDAC1 (Homo sapiens)
PPARG (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 68.88 Quite High
agonist 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 53 50.00 Quite Low
Targeted Disruption 1 11.84 Low Low
Cancer 31 5.00 Very Low Very Low Very Low
Microsatellite Instability 7 5.00 Very Low Very Low Very Low
Repression 6 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Cirrhosis 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Metabolic Syndrome 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with the MeDIP data, HDAC1 was tightly bound to PPARG promoter, whereas RNA-Polymerase II (RNAPol-II) and its phosphorylated form (P-RNAPol-II) were barely present in untreated HCT116 cells (Figure 3, panel A).
HDAC1 Binding (bound) of PPARG
1) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2997072 Disease Relevance 0 Pain Relevance 0.03

General Comments

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