INT348595

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PPARG) enzyme binding (PPARG) DNA binding (PPARG)
lipid metabolic process (PPARG) cytoplasm (PPARG) cytosol (PPARG)
Anatomy Link Frequency
finger 1
PPARG (Homo sapiens)
ZACN (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 4 41.60 Quite Low
antagonist 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 53 98.76 Very High Very High Very High
Repression 6 82.64 Quite High
Cirrhosis 3 32.36 Quite Low
Metabolic Syndrome 2 17.40 Low Low
Diabetes Mellitus 1 15.80 Low Low
Cancer 31 8.72 Low Low
Microsatellite Instability 7 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, we propose a novel regulatory model in which an unmethylated (or partially methylated) PPARG core promoter region is normally recognized by unknown transcriptional activators, among which only the zinc-finger protein ZAC has been identified so far in CRC cells [23].
PPARG Binding (recognized) of ZAC in finger associated with colon cancer
1) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2997072 Disease Relevance 0.38 Pain Relevance 0

General Comments

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