INT348755

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Plat) extracellular space (Plat) extracellular region (Plat)
structural molecule activity (Cldn5) plasma membrane (Cldn5) cytoplasm (Plat)
Anatomy Link Frequency
endothelial cells 2
Plat (Mus musculus)
Cldn5 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 12 77.20 Quite High
metalloproteinase 14 74.08 Quite High
Inflammation 1 28.40 Quite Low
cva 6 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Restless leg syndrome 1 5.00 Very Low Very Low Very Low
Neurobehavioral 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 4 86.52 High High
Cv General 4 Under Development 6 77.92 Quite High
Cv Unclassified Under Development 2 76.52 Quite High
Disease 3 57.32 Quite High
Brain Hemorrhage 9 50.00 Quite Low
Targeted Disruption 1 43.92 Quite Low
Injury 7 41.08 Quite Low
INFLAMMATION 1 28.40 Quite Low
Cerebral Edema 10 24.44 Low Low
Stroke 9 15.68 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results showed that the expression of claudin-5 was altered by tPA, which results in the disruption of the barrier permeability of neural vascular endothelial cells, and whose disruption was prevented by cilostazol.
tPA Regulation (altered) of Gene_expression (expression) of claudin-5 in endothelial cells
1) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2997776 Disease Relevance 0.45 Pain Relevance 0.25

General Comments

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