INT348758

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 3
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.42
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Plat, LDHA) cytosol (LDHA) peptidase activity (Plat)
extracellular space (Plat) small molecule metabolic process (LDHA) oxidoreductase activity (LDHA)
Anatomy Link Frequency
endothelial cells 1
pericytes 1
astrocytes 1
Plat (Mus musculus)
LDHA (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 36 50.00 Quite Low
Eae 3 34.68 Quite Low
cva 18 18.64 Low Low
metalloproteinase 42 5.00 Very Low Very Low Very Low
aspirin 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Restless leg syndrome 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Neurobehavioral 3 5.00 Very Low Very Low Very Low
Immobilon 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 21 71.52 Quite High
Cerebral Edema 30 65.92 Quite High
Brain Hemorrhage 27 50.00 Quite Low
Brain Injury 9 33.56 Quite Low
Cv General 4 Under Development 18 18.64 Low Low
Hemorrhage 6 13.96 Low Low
Stroke 27 5.00 Very Low Very Low Very Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Infarction 9 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In endothelial cells, the LDH level was not changed by 3, 10, 30, and 100 µg/ml of tPA (data not shown) but was increased by 300-µg/ml tPA, and the increase was significantly reduced by the combination of 10 to 100 µM of cilostazol in a concentration-dependent manner (Fig. 6A).
tPA Neg (not) Positive_regulation (increased) of LDH in endothelial cells
1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2997776 Disease Relevance 0.19 Pain Relevance 0
On the other hand, in pericytes and astrocytes, the LDH level was not changed by 3, 10, 30, and 100 µg/ml of tPA (data not shown) but increased by 300-µg/ml tPA.
tPA Neg (not) Positive_regulation (increased) of LDH in pericytes
2) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2997776 Disease Relevance 0.11 Pain Relevance 0
On the other hand, in pericytes and astrocytes, the LDH level was not changed by 3, 10, 30, and 100 µg/ml of tPA (data not shown) but increased by 300-µg/ml tPA.
tPA Neg (not) Positive_regulation (increased) of LDH in astrocytes
3) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2997776 Disease Relevance 0.11 Pain Relevance 0

General Comments

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