INT348772

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Context Info
Confidence 0.61
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4) plasma membrane (Tlr4) intracellular (Tlr4)
cytoplasm (Tlr4)
Tlr4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tolerance 6 99.00 Very High Very High Very High
cytokine 13 82.20 Quite High
Inflammation 33 81.80 Quite High
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sepsis 63 99.76 Very High Very High Very High
Obesity 20 90.24 High High
INFLAMMATION 41 81.80 Quite High
Insulin Resistance 20 5.00 Very Low Very Low Very Low
Stress 13 5.00 Very Low Very Low Very Low
Hyperglycemia 4 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Hypoglycemia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sepsis induced an increase in the expression/activation of TLR4 and its downstream signaling JNK and IKK/NF-?
Positive_regulation (increase) of Positive_regulation (activation) of TLR4 associated with sepsis
1) Confidence 0.61 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2997789 Disease Relevance 0.72 Pain Relevance 0.21

General Comments

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