INT348789

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.46
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (MYD88, Tlr4) plasma membrane (MYD88, Tlr4) intracellular (MYD88, Tlr4)
cytoplasm (MYD88, Tlr4) cytosol (MYD88)
MYD88 (Homo sapiens)
Tlr4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 33 87.52 High High
cytokine 13 81.44 Quite High
Inflammatory response 4 80.52 Quite High
tolerance 6 18.88 Low Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sepsis 63 98.66 Very High Very High Very High
Obesity 20 95.56 Very High Very High Very High
INFLAMMATION 41 87.52 High High
Insulin Resistance 20 80.56 Quite High
Stress 13 5.00 Very Low Very Low Very Low
Hyperglycemia 4 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Hypoglycemia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fig. 3 shows that sepsis induced TLR4 protein levels and activation, as demonstrated by an increase in TLR4/MyD88 interaction in the three tissues investigated, and atorvastatin reduced this early step of TLR4 activation and also TLR4 expression (Fig. 3A–C).
Positive_regulation (increase) of MyD88 Binding (interaction) of TLR4 associated with sepsis
1) Confidence 0.46 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2997789 Disease Relevance 0.93 Pain Relevance 0.20

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox