INT348918

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (CSPG4) plasma membrane (CSPG4) intracellular (CSPG4)
signal transducer activity (CSPG4)
Anatomy Link Frequency
knee 2
CSPG4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 47 97.76 Very High Very High Very High
Inflammation 2 62.60 Quite High
corticosteroid 22 50.00 Quite Low
Pain 22 44.68 Quite Low
cINOD 2 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
Pain scale 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
flare ups 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 46 97.76 Very High Very High Very High
Nociception 1 63.64 Quite High
INFLAMMATION 3 62.60 Quite High
Pain 22 44.68 Quite Low
Adverse Drug Reaction 1 20.64 Low Low
Hip Osteoarthritis 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Chondrocalcinosis 2 5.00 Very Low Very Low Very Low
Lumbar Puncture Related Headaches 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The authors concluded that given the lack of a superior effectiveness of HMW HA over LMW HA and the increased risk of local adverse events associated with the first, it is better to use intra-articular LMW HA in patients with OA of the knee in clinical research or practice.
Negative_regulation (lack) of Negative_regulation (effectiveness) of HMW HA in knee associated with osteoarthritis
1) Confidence 0.06 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2998460 Disease Relevance 0.59 Pain Relevance 0.20

General Comments

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