INT34903

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Context Info
Confidence 0.18
First Reported 1986
Last Reported 1986
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL2) extracellular region (IL2) cell adhesion (IL2)
cell-cell signaling (IL2)
Anatomy Link Frequency
T lymphocyte 2
CALM1 (Homo sapiens)
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 3 99.92 Very High Very High Very High
Kinase C 1 63.56 Quite High
local anesthetic 1 50.44 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The data support the hypothesis that cyclosporine may be an antagonist of calmodulin that selectively blocks early events in T lymphocyte activation leading to IL-2 synthesis, but does not inhibit the expression or function of the IL-2 receptor.
calmodulin Negative_regulation (inhibit) of Gene_expression (expression) of IL-2 in T lymphocyte associated with antagonist
1) Confidence 0.18 Published 1986 Journal Transplantation Section Abstract Doc Link 3097893 Disease Relevance 0 Pain Relevance 0.20

General Comments

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