INT349079

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD80, Cd86) intracellular (CD80) cell-cell signaling (CD80)
Anatomy Link Frequency
T cell 1
CD80 (Homo sapiens)
Cd86 (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 2 25.60 Quite Low
cytokine 2 12.16 Low Low
abatacept 5 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Graft Vs Host Disease 2 50.00 Quite Low
Adverse Drug Reaction 2 42.60 Quite Low
Renal Failure 15 35.64 Quite Low
Apoptosis 1 20.08 Low Low
Diabetes Mellitus 5 15.44 Low Low
Hyperlipidemia 2 14.60 Low Low
Hypertension 2 13.84 Low Low
Infection 6 8.68 Low Low
Cardiovascular Disease 1 8.08 Low Low
Lymphoproliferative Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This signal is mediated by the interaction of CD80 (B7.1) and CD86 (B7.2) on antigen-presenting cells with specific T cell receptors (CD28 and its homolog, cytotoxic T lymphocyte-associated antigen 4 [CTLA4]).
CD80 Binding (interaction) of B7.2 in T cell
1) Confidence 0.22 Published 2010 Journal Drug Design, Development and Therapy Section Body Doc Link PMC2998809 Disease Relevance 0 Pain Relevance 0

General Comments

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