INT349103

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Context Info
Confidence 0.29
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.07
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Hyal1) cell death (Hyal1) extracellular region (Hyal1)
carbohydrate metabolic process (Hyal1) lysosome (Hyal1) cytoplasm (Hyal1)
Anatomy Link Frequency
plasma 1
Hyal1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 99.60 Very High Very High Very High
Inflammatory response 2 24.24 Low Low
anesthesia 4 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Proteinuria 10 99.96 Very High Very High Very High
INFLAMMATION 10 99.60 Very High Very High Very High
Atherosclerosis 26 89.76 High High
Hyperlipoproteinemia Type Ii 2 85.44 High High
Albuminuria 2 73.64 Quite High
Disorder Of Lipid Metabolism 6 50.00 Quite Low
Pressure And Volume Under Development 2 39.28 Quite Low
Atherosclerotic Plaque 4 26.48 Quite Low
Disease Progression 6 5.00 Very Low Very Low Very Low
Dyslipidemia /

Combined Dyslipidemia

4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, in animals and patients with DM1, both characterized by increased risk for development of proteinuria, plasma hyaluronidase levels are elevated and associated with decreased endothelial surface layer, underscoring potential clinical relevance [25], [29].


plasma hyaluronidase Binding (associated) of in plasma associated with proteinuria
1) Confidence 0.29 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2999536 Disease Relevance 0.44 Pain Relevance 0
At the same time, both inactivated and active hyaluronidase were associated with pro-inflammatory changes [32].
hyaluronidase Binding (associated) of associated with inflammation
2) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2999536 Disease Relevance 0.63 Pain Relevance 0.09

General Comments

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