INT349130

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Gria1, Shisa9) cytosol (Gria1) endoplasmic reticulum (Gria1)
molecular_function (Shisa9) protein complex (Gria1)
Gria1 (Rattus norvegicus)
Shisa9 (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 17 99.56 Very High Very High Very High
Hippocampus 48 85.76 High High
amygdala 24 84.44 Quite High
depression 4 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
antidepressant 2 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 75 89.56 High High
Depression 4 5.00 Very Low Very Low Very Low
Cognitive Disorder 3 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low
Affective Disorder 2 5.00 Very Low Very Low Very Low
Overactive Bladder 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The phosphorylation on Ser831-GluA1 is thought to affect plasticity by increasing the AMPAR channel conductance [17] and potentiating GluA1-mediated current [18], [19], whereas the phosphorylation of Ser845-GluA1 accompanies surface insertion of AMPARs receptors at in extra synaptic sites, which provides a pool of receptors available for LTP induction [20], [21].
Phosphorylation (phosphorylation) of GluA1 Positive_regulation (increasing) of AMPAR associated with long-term potentiation
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2999558 Disease Relevance 0.49 Pain Relevance 0.52

General Comments

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