INT349219

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTPRC, SLC3A2) carbohydrate metabolic process (SLC3A2) transmembrane transport (SLC3A2)
Anatomy Link Frequency
plasma 2
PTPRC (Homo sapiens)
SLC3A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Alveolar Proteinosis 35 79.36 Quite High
Disease 1 73.20 Quite High
Hyperammonemia 1 70.96 Quite High
Failure To Thrive 1 67.52 Quite High
Renal Disease 2 66.00 Quite High
Osteoporosis 1 64.48 Quite High
Congenital Anomalies 2 54.64 Quite High
Interstitial Lung Diseases 1 44.32 Quite Low
Respiratory Failure 5 20.16 Low Low
Pneumothorax 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The defect affects transport system y+L, a member of the large group of heterodimeric amino acid transporters formed by a light subunit, which may be either y+LAT1 (encoded by the SLC7A7 gene) or y+LAT2 (SLC7A6 gene), and a glycoprotein (4F2 hc/CD98 hc) that is necessary for the correct expression of the transporter in the plasma membrane [2].
glycoprotein Positive_regulation (necessary) of Gene_expression (expression) of 4F2 hc in plasma
1) Confidence 0.11 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2999609 Disease Relevance 0.53 Pain Relevance 0

General Comments

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