INT349300

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Context Info
Confidence 0.75
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 8
Disease Relevance 8.65
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PARK7) peptidase activity (PARK7) mitochondrion (PARK7)
mRNA binding (PARK7) mitochondrion organization (PARK7) nucleus (PARK7)
PARK7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 24 83.28 Quite High
imagery 40 58.00 Quite High
glial activation 8 50.72 Quite High
cytokine 16 44.88 Quite Low
Substantia nigra 32 43.48 Quite Low
positron emission tomography 24 5.00 Very Low Very Low Very Low
Neuritis 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 920 99.24 Very High Very High Very High
Stress 32 89.80 High High
Neurodegenerative Disease 48 86.00 High High
INFLAMMATION 24 83.28 Quite High
Stroke 8 76.64 Quite High
Familial Amyloidotic Polyneuropathy 8 76.16 Quite High
Skin Cancer 8 74.68 Quite High
Breast Cancer 8 74.28 Quite High
Disease Progression 24 48.56 Quite Low
Necrosis 8 39.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with this, we observed that both monomer and aggregates of DJ-1 were abundantly present in the CSF, and our semi-quantitative immunoblot analysis revealed that CSF-1 DJ-1 monomer levels were significantly increased in PD compared to those in non-PD controls [33].
Gene_expression (present) of DJ-1 associated with disease
1) Confidence 0.75 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000080 Disease Relevance 1.55 Pain Relevance 0
-synuclein nor DJ-1 is satisfactory as a single biological fluid biomarker for PD.
Gene_expression (synuclein) of DJ-1 associated with disease
2) Confidence 0.65 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000080 Disease Relevance 1.44 Pain Relevance 0.12
Maita et al. examined DJ-1 levels using a DJ-1 ELISA kit in PD cases and age-matched controls, but did not find a significant difference in the levels of secreted DJ-1 between these groups or correlations of DJ-1 levels with age and clinical severity [35].
Gene_expression (levels) of DJ-1 associated with disease
3) Confidence 0.65 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000080 Disease Relevance 0.87 Pain Relevance 0
-synuclein and DJ-1 levels as biomarkers for PD.
Gene_expression (synuclein) of DJ-1 associated with disease
4) Confidence 0.65 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000080 Disease Relevance 0.89 Pain Relevance 0
The results showed that CSF DJ-1 and ?
Gene_expression (showed) of DJ-1
5) Confidence 0.65 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000080 Disease Relevance 0.83 Pain Relevance 0
-synuclein and DJ-1 levels as biomarkers for PD.
Gene_expression (levels) of DJ-1 associated with disease
6) Confidence 0.65 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000080 Disease Relevance 0.89 Pain Relevance 0
Maita et al. examined DJ-1 levels using a DJ-1 ELISA kit in PD cases and age-matched controls, but did not find a significant difference in the levels of secreted DJ-1 between these groups or correlations of DJ-1 levels with age and clinical severity [35].
Gene_expression (levels) of DJ-1 associated with disease
7) Confidence 0.57 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000080 Disease Relevance 1.22 Pain Relevance 0
-synuclein levels did not differ in PD cases compared to age-matched controls and AD cases, and concluded that, unlike in the CSF, total DJ-1 or ?
Gene_expression (total) of DJ-1 associated with disease
8) Confidence 0.57 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000080 Disease Relevance 0.96 Pain Relevance 0

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