INT349302

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Context Info
Confidence 0.78
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.09
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PARK7) peptidase activity (PARK7) mitochondrion (PARK7)
mRNA binding (PARK7) mitochondrion organization (PARK7) nucleus (PARK7)
Anatomy Link Frequency
Blood 1
PARK7 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 15 5.00 Very Low Very Low Very Low
Substantia nigra 12 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
positron emission tomography 9 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Neuritis 3 5.00 Very Low Very Low Very Low
glial activation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 345 99.24 Very High Very High Very High
Breast Cancer 3 98.68 Very High Very High Very High
Skin Cancer 3 98.08 Very High Very High Very High
Familial Amyloidotic Polyneuropathy 3 97.68 Very High Very High Very High
Stress 12 96.60 Very High Very High Very High
Stroke 3 96.04 Very High Very High Very High
Disease Progression 9 93.88 High High
Neurodegenerative Disease 18 74.96 Quite High
Drug Induced Neurotoxicity 3 32.96 Quite Low
Parkinson's Disease 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DJ-1 is secreted into the serum of patients with breast cancer, melanoma, familial amyloidotic polyneuropathy, and stroke [29].
Localization (secreted) of DJ-1 associated with familial amyloidotic polyneuropathy, stroke, breast cancer and skin cancer
1) Confidence 0.78 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000080 Disease Relevance 1.26 Pain Relevance 0
Evaluation of CSF and Blood DJ-1 as a Biomarker of PD
Localization (Evaluation) of DJ-1 in Blood associated with disease
2) Confidence 0.73 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000080 Disease Relevance 0.88 Pain Relevance 0
Maita et al. examined DJ-1 levels using a DJ-1 ELISA kit in PD cases and age-matched controls, but did not find a significant difference in the levels of secreted DJ-1 between these groups or correlations of DJ-1 levels with age and clinical severity [35].
Localization (secreted) of DJ-1 associated with disease
3) Confidence 0.68 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000080 Disease Relevance 0.95 Pain Relevance 0

General Comments

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