INT349312

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Bcar1) plasma membrane (Bcar1) cytoplasm (Bcar1)
Anatomy Link Frequency
brain 2
Bcar1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 6 29.52 Quite Low
Dopamine 10 8.16 Low Low
Substantia nigra 7 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
Ventral tegmentum 3 5.00 Very Low Very Low Very Low
dopamine receptor 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 6 100.00 Very High Very High Very High
Parkinson's Disease 8 97.76 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 78.32 Quite High
Disease 42 69.36 Quite High
INFLAMMATION 7 29.52 Quite Low
Neurodegenerative Disease 9 5.88 Low Low
Death 6 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 3 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In an azidothymidine neurotoxicity model in rats, mildronate suppressed the neuroinflammatory and apoptotic processes in brain tissue by protecting the abnormal expression of cytochrome oxidase c, caspase-3, iNOS, cellular apoptosis susceptibility (CAS) protein and glial fibrillary acidic protein (GFAP) [37].
Regulation (abnormal) of Gene_expression (expression) of CAS in brain associated with parkinson's disease and apoptosis
1) Confidence 0.07 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000094 Disease Relevance 0.58 Pain Relevance 0

General Comments

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