INT34939

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Context Info
Confidence 0.45
First Reported 1987
Last Reported 2005
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.00
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Plat) extracellular space (Plat) extracellular region (Plat)
molecular_function (Plat) cytoplasm (Plat)
Anatomy Link Frequency
sciatic nerve 2
Plat (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Sciatic nerve 1 99.12 Very High Very High Very High
ischemia 1 97.40 Very High Very High Very High
Neuropathic pain 1 95.72 Very High Very High Very High
Angina 2 85.76 High High
Peripheral nerve injury 1 75.00 Quite High
Root ganglion neuron 1 75.00 Quite High
neuralgia 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 5 97.84 Very High Very High Very High
Neuropathic Pain 1 95.72 Very High Very High Very High
Complex Regional Pain Syndromes 1 85.28 High High
Injury 3 79.44 Quite High
Nervous System Injury 2 75.00 Quite High
Ganglion Cysts 1 75.00 Quite High
Cv General 3 Under Development 1 74.80 Quite High
Stress 1 72.00 Quite High
Myocardial Infarction 1 69.20 Quite High
Hypertension 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased levels of an endogenous inhibitor of tissue-plasminogen activator (t-PA) have been thought to relate to the genesis of acute myocardial ischemia.
Positive_regulation (Increased) of Negative_regulation (inhibitor) of t-PA associated with coronary artery disease and ischemia
1) Confidence 0.45 Published 1987 Journal J. Am. Coll. Cardiol. Section Abstract Doc Link 3100598 Disease Relevance 0.60 Pain Relevance 0.21
Here we examined whether the plasminogen activator inhibitor-1 and -2 (PAI-1 and PAI-2) mRNA, endogenous inhibitors of tPA and uPA, are induced in the DRG following sciatic nerve transection.
Spec (whether) Positive_regulation (induced) of Spec (whether) Negative_regulation (inhibitors) of tPA in sciatic nerve associated with sciatic nerve
2) Confidence 0.05 Published 2005 Journal Neuroscience Section Abstract Doc Link 15780477 Disease Relevance 0.40 Pain Relevance 0.22

General Comments

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