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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CISH) intracellular (CISH) molecular_function (CISH)
cellular_component (CISH)
CISH (Homo sapiens)
Pain Link Frequency Relevance Heat
cerebral cortex 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 7 53.12 Quite High
Tremor 4 50.00 Quite Low
Ataxia 3 50.00 Quite Low
Disease 7 39.76 Quite Low
Toxicity 10 38.04 Quite Low
Intellectual Impairment 4 10.60 Low Low
Fragile X Syndrome 2 8.68 Low Low
Necrosis 2 8.16 Low Low
Syndrome 14 5.00 Very Low Very Low Very Low
Lifespan 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A third possibility, which to date has only been explored in vitro [26], [27], is that the premutation range CGG repeat itself could lead to alterations in the local DNA and/or chromatin structure at the FMR1 locus, stimulating increased basal transcription in cis.
Positive_regulation (increased) of Transcription (transcription) of cis
1) Confidence 0.03 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC3000359 Disease Relevance 0.05 Pain Relevance 0

General Comments

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